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  • Cambridge
  • £3,408 monthly starting salary after tax (Grade 7)
    • Contract
  • 10 Mar 2020

About the team/job

We are seeking an experienced project leader for activities and resources supporting model organism genomics at the European Bioinformatics Institute (EMBL-EBI).

Mice, rats, zebrafish, flies, worms and yeast are studied extensively by scientists around the world to gain fundamental insights into human biology.  The Alliance of Genome Resources (AGR, www.alliancegenome.org) is a major new initiative to develop shared infrastructure, analysis pipelines and data curation workflows for 6 major Model Organism Databases(MODs) and the Gene Ontology (GO). WormBase (www.wormbase.org), a founding member of the Alliance, is dedicated to providing integrated information on the genetics and genomics of the model organism Caenorhabditis elegans.

You will lead a team that acts as the genomics and hub for AGR and WormBase. The team’s responsibilities range from designing and deploying large-scale data integration and genome analysis pipelines, to curating the canonical reference genome and annotation for C. elegans. The team also collaborates closely with the Wellcome Sanger Institute to produce WormBase ParaSite (parasite.wormbase.org), which uses the Ensembl platform (www.ensembl.org) to provide access to hundreds of genomes for parasitic worms that damage human health and food supply.

You will be part of the Eukaryotic Annotation Team (led by Kevin Howe), which itself is part of a wider cluster of resources that includes Ensembl (led by Paul Flicek). EMBL-EBI is part of the European Molecular Biology Laboratory (EMBL) and is Europe's leading provider of information services to biological researchers in academia and industry.

Your role

Under the supervision of the Team Leader, will operationally lead our contribution to the Alliance of Genome Resources, WormBase, and WormBase ParaSite. You will work closely with peers at international partner sites to ensure that the overall goals of these projects are met.

Your specific responsibilities will include:

  • Line management of a team of 5-7 bioinformaticians, developers and curators
  • Leading the development of genomics data analysis and integration pipelines for the Alliance of Genome Resources and WormBase
  • Project management for the provision of parasitic worm genomics data via the Ensembl platform 
  • Leadership of the curation effort for the reference genome and annotation for C. elegansand selected other nematodes
  • Engagement with relevant scientific communities
  • Writing publications and reports
  • Representing the project(s) at meetings and conferences

You have

You will hold a PhD or equivalent in bioinformatics or a related field and have ideally three years post-graduate professional experience. Specifically, you will have:

  • Broad practical knowledge of genomic analysis techniques and tools
  • Detailed knowledge of genome annotation methodologies
  • Practical experience with using databases for modelling complex biological data (knowledge of graph databases will be considered a plus)
  • Excellent written and verbal communication skills
  • Previous experience with management or mentoring

You might also have

The ideal candidate might also have experience with:

  • Model organism genetics
  • Working with the Ensembl platform 
  • Writing software in Python or Perl
  • Working within international consortia
  • Formal project management tools/techniques

 For additional information and the instruction on how to apply, please click the Apply button above.

  • Cambridge
  • £3,408 monthly starting salary after tax (Grade 7)
    • Contract
  • 10 Mar 2020

About the team/job

We are seeking an experienced project leader for activities and resources supporting model organism genomics at the European Bioinformatics Institute (EMBL-EBI).

Mice, rats, zebrafish, flies, worms and yeast are studied extensively by scientists around the world to gain fundamental insights into human biology.  The Alliance of Genome Resources (AGR, www.alliancegenome.org) is a major new initiative to develop shared infrastructure, analysis pipelines and data curation workflows for 6 major Model Organism Databases(MODs) and the Gene Ontology (GO). WormBase (www.wormbase.org), a founding member of the Alliance, is dedicated to providing integrated information on the genetics and genomics of the model organism Caenorhabditis elegans.

You will lead a team that acts as the genomics and hub for AGR and WormBase. The team’s responsibilities range from designing and deploying large-scale data integration and genome analysis pipelines, to curating the canonical reference genome and annotation for C. elegans. The team also collaborates closely with the Wellcome Sanger Institute to produce WormBase ParaSite (parasite.wormbase.org), which uses the Ensembl platform (www.ensembl.org) to provide access to hundreds of genomes for parasitic worms that damage human health and food supply.

You will be part of the Eukaryotic Annotation Team (led by Kevin Howe), which itself is part of a wider cluster of resources that includes Ensembl (led by Paul Flicek). EMBL-EBI is part of the European Molecular Biology Laboratory (EMBL) and is Europe's leading provider of information services to biological researchers in academia and industry.

Your role

Under the supervision of the Team Leader, will operationally lead our contribution to the Alliance of Genome Resources, WormBase, and WormBase ParaSite. You will work closely with peers at international partner sites to ensure that the overall goals of these projects are met.

Your specific responsibilities will include:

  • Line management of a team of 5-7 bioinformaticians, developers and curators
  • Leading the development of genomics data analysis and integration pipelines for the Alliance of Genome Resources and WormBase
  • Project management for the provision of parasitic worm genomics data via the Ensembl platform 
  • Leadership of the curation effort for the reference genome and annotation for C. elegansand selected other nematodes
  • Engagement with relevant scientific communities
  • Writing publications and reports
  • Representing the project(s) at meetings and conferences

You have

You will hold a PhD or equivalent in bioinformatics or a related field and have ideally three years post-graduate professional experience. Specifically, you will have:

  • Broad practical knowledge of genomic analysis techniques and tools
  • Detailed knowledge of genome annotation methodologies
  • Practical experience with using databases for modelling complex biological data (knowledge of graph databases will be considered a plus)
  • Excellent written and verbal communication skills
  • Previous experience with management or mentoring

You might also have

The ideal candidate might also have experience with:

  • Model organism genetics
  • Working with the Ensembl platform 
  • Writing software in Python or Perl
  • Working within international consortia
  • Formal project management tools/techniques

 For additional information and the instruction on how to apply, please click the Apply button above.

  • London, England, United Kingdom
  • Competitive
    • Permanent
  • 10 Mar 2020
Consultant (SQL, Java and/or C#)- Technical Implementation Services (Charles River); Officer
Charles River provides an end-to-end solution to automate front and middle office investment management functions across asset classes on a single platform. Delivered as a hosted service, the solution improves data quality and investment professional productivity, controls risk and lowers technology costs. Charles River serves more than 350 investment firms in over 40 countries in the institutional asset and fund management, private wealth, alternative investments, insurance, banking, and pension markets. Charles River were acquired by State Street in October 2018.

The Role
  • Assist, from a technical standpoint, in the implementation of a sophisticated trade order management and compliance monitoring systems to the fund management industry
  • Provide technical consultancy services for clients and their CRD Account Managers including; install, configure and test software; problem investigation; database configuration, tracing and performance analysis.
  • Provide technical consultancy services for systems integration
  • Design and development of solutions for additional Client requirements
  • This role involves extensive travel and will involve spending time working on Client sites both in London and the EMEA region.

Skills/Experience/Qualifications Required:

Technical:
  • Experience in at least one major DBMS (MS SQL Server or Oracle), including installation, configuration and development.
  • Good knowledge and experience of
    • PL/SQL or TransactSQL (MS SQL Server)
    • Complex SQL
    • Debugging and optimization
  • System interfacing and integration
  • Commercial, real life development experience in Java and/or C#.
  • Development experience in some or all of the following would be an advantage
    • Web Services
    • Crystal Reports
    • XML Messaging
    • Excel VBA
    • Perl
    • .NET

Business/Personal
  • Exposure to working in Financial services; front- or middle-office, or fund management business areas ideal.
  • Experience dealing with users or clients from either a technical or business area. Desire to work in Client facing environment.
  • Some knowledge of;
    • Project phasing and reporting
    • On-site delivery
    • Systems support
    • Operational procedures
    • Batch processing
    • System sizing and capacity planning
    • System backup, contingency and disaster recovery
    • Regional roll outs
  • Third level qualification essential ideally a Technical Bachelors Degree.
  • Fluency in a European language highly desirable.
  • London, England, United Kingdom
  • Competitive
    • Permanent
  • 10 Mar 2020
Consultant (SQL, Java and/or C#)- Technical Implementation Services (Charles River); Officer
Charles River provides an end-to-end solution to automate front and middle office investment management functions across asset classes on a single platform. Delivered as a hosted service, the solution improves data quality and investment professional productivity, controls risk and lowers technology costs. Charles River serves more than 350 investment firms in over 40 countries in the institutional asset and fund management, private wealth, alternative investments, insurance, banking, and pension markets. Charles River were acquired by State Street in October 2018.

The Role
  • Assist, from a technical standpoint, in the implementation of a sophisticated trade order management and compliance monitoring systems to the fund management industry
  • Provide technical consultancy services for clients and their CRD Account Managers including; install, configure and test software; problem investigation; database configuration, tracing and performance analysis.
  • Provide technical consultancy services for systems integration
  • Design and development of solutions for additional Client requirements
  • This role involves extensive travel and will involve spending time working on Client sites both in London and the EMEA region.

Skills/Experience/Qualifications Required:

Technical:
  • Experience in at least one major DBMS (MS SQL Server or Oracle), including installation, configuration and development.
  • Good knowledge and experience of
    • PL/SQL or TransactSQL (MS SQL Server)
    • Complex SQL
    • Debugging and optimization
  • System interfacing and integration
  • Commercial, real life development experience in Java and/or C#.
  • Development experience in some or all of the following would be an advantage
    • Web Services
    • Crystal Reports
    • XML Messaging
    • Excel VBA
    • Perl
    • .NET

Business/Personal
  • Exposure to working in Financial services; front- or middle-office, or fund management business areas ideal.
  • Experience dealing with users or clients from either a technical or business area. Desire to work in Client facing environment.
  • Some knowledge of;
    • Project phasing and reporting
    • On-site delivery
    • Systems support
    • Operational procedures
    • Batch processing
    • System sizing and capacity planning
    • System backup, contingency and disaster recovery
    • Regional roll outs
  • Third level qualification essential ideally a Technical Bachelors Degree.
  • Fluency in a European language highly desirable.
  • London, England, United Kingdom
  • Competitive
    • Permanent
  • 10 Mar 2020
Senior Consultant (SQL, Java and/or C#) - Tech. Implementation Svcs (Charles River); AVP
Charles River provides an end-to-end solution to automate front and middle office investment management functions across asset classes on a single platform. Delivered as a hosted service, the solution improves data quality and investment professional productivity, controls risk and lowers technology costs. Charles River serves more than 350 investment firms in over 40 countries in the institutional asset and fund management, private wealth, alternative investments, insurance, banking, and pension markets. Charles River were acquired by State Street in October 2018.

The Background :

The ideal candidate will have a predominantly technical background implementing major fund management and/or banking software applications, preferably within a front office environment. They will also have a good understanding of the fund management and/or front-office terminology and operations.

The Role
  • Assist, from a technical standpoint, in the implementation of a sophisticated trade order management and compliance monitoring systems to the fund management industry
  • Provide technical consultancy services for clients and their CRD Account Managers including; install, configure and test software; problem investigation; database configuration, tracing and performance analysis.
  • Provide technical consultancy services for systems integration
  • Design and development of solutions for additional Client requirements
  • This role involves extensive travel and will involve spending time working on Client sites both in London and the EMEA region.

Skills/Experience/Qualifications Required:

Technical:
  • Experience in at least one major DBMS (MS SQL Server or Oracle), including installation, configuration and development.
  • Good knowledge and experience of
    • PL/SQL or TransactSQL (MS SQL Server)
    • Complex SQL
    • Debugging and optimization
  • System interfacing and integration
  • Proven, substantial, development experience in Java and/or C#.
  • Development experience in some or all of the following would be an advantage
    • Web Services
    • Crystal Reports
    • XML Messaging
    • Excel VBA
    • Perl
    • .NET
Business/Personal
  • Exposure to working in Financial services; front- or middle-office, or fund management business areas ideal
  • Experience dealing with users or clients from either a technical or business area.
  • Comfortable making presentations covering business, technical or sales.
  • Detailed knowledge of;
    • Project phasing and reporting
    • On-site delivery
    • Systems support
    • Operational procedures
    • Batch processing
    • System sizing and capacity planning
    • System backup, contingency and disaster recovery
    • Regional roll outs
  • Third level qualification essential ideally a Technical Bachelors Degree.
  • Fluency in a European language highly desirable.
  • London, England, United Kingdom
  • Competitive
    • Permanent
  • 10 Mar 2020
Senior Consultant (SQL, Java and/or C#) - Tech. Implementation Svcs (Charles River); AVP
Charles River provides an end-to-end solution to automate front and middle office investment management functions across asset classes on a single platform. Delivered as a hosted service, the solution improves data quality and investment professional productivity, controls risk and lowers technology costs. Charles River serves more than 350 investment firms in over 40 countries in the institutional asset and fund management, private wealth, alternative investments, insurance, banking, and pension markets. Charles River were acquired by State Street in October 2018.

The Background :

The ideal candidate will have a predominantly technical background implementing major fund management and/or banking software applications, preferably within a front office environment. They will also have a good understanding of the fund management and/or front-office terminology and operations.

The Role
  • Assist, from a technical standpoint, in the implementation of a sophisticated trade order management and compliance monitoring systems to the fund management industry
  • Provide technical consultancy services for clients and their CRD Account Managers including; install, configure and test software; problem investigation; database configuration, tracing and performance analysis.
  • Provide technical consultancy services for systems integration
  • Design and development of solutions for additional Client requirements
  • This role involves extensive travel and will involve spending time working on Client sites both in London and the EMEA region.

Skills/Experience/Qualifications Required:

Technical:
  • Experience in at least one major DBMS (MS SQL Server or Oracle), including installation, configuration and development.
  • Good knowledge and experience of
    • PL/SQL or TransactSQL (MS SQL Server)
    • Complex SQL
    • Debugging and optimization
  • System interfacing and integration
  • Proven, substantial, development experience in Java and/or C#.
  • Development experience in some or all of the following would be an advantage
    • Web Services
    • Crystal Reports
    • XML Messaging
    • Excel VBA
    • Perl
    • .NET
Business/Personal
  • Exposure to working in Financial services; front- or middle-office, or fund management business areas ideal
  • Experience dealing with users or clients from either a technical or business area.
  • Comfortable making presentations covering business, technical or sales.
  • Detailed knowledge of;
    • Project phasing and reporting
    • On-site delivery
    • Systems support
    • Operational procedures
    • Batch processing
    • System sizing and capacity planning
    • System backup, contingency and disaster recovery
    • Regional roll outs
  • Third level qualification essential ideally a Technical Bachelors Degree.
  • Fluency in a European language highly desirable.
  • Hinxton, UK
  • 10 Mar 2020

Job description

Ensembl (http://www.ensembl.org/) is one of the leading large-scale bioinformatics projects for genome annotation. We import ‘big’ amounts of ‘data’ from various archives (genome sequences, variation archives, etc), to create summaries (e.g. gene annotations, whole-genome alignments, gene trees, regulatory elements, etc.). We redistribute these freely to researchers across the world.

We are looking for an enthusiastic software developer to join our team. You will be responsible for developing and maintaining the very core of the apis used by Ensembl

Your role

You will

  • Design and develop APIs which are consumed by internal as well as external users for their computational workflows
  • Support and maintain the existing open source code
  • Co-ordinate answers for user queries
  • Contribute to modelling for seamless access of structured/non-structured data types
  • Help in development and maintenance of proprietary HPC based workflow manager system

You have

  • MSc or Phd or equivalent experience, in computer science/bioinformatics (or related field), large software development projects
  • Experience in object oriented Perl programming
  • Experience in database modelling and SQL
  • Ability to work on parallel tasks
  • Good communication skills
  • Ability to work independently while also interacting in a team environment
  • Attitude to contribute to a larger scientific cause

You might also have

  • Experience in development of scientific computational workflows
  • Working knowledge of HPC based workflows managers
  • Experience in working in large scientific projects

Why join us

At EMBL-EBI, we help scientists realise the potential of ‘big data’ in biology by enabling them to exploit complex information to make discoveries that benefit mankind.

Working for EMBL-EBI gives you an opportunity to apply your skills and energy for the greater good.

As part of the European Molecular Biology Laboratory (EMBL), we are a non-profit, intergovernmental organisation funded by over 27 member states and two associate member states.

We are located on the Wellcome Genome Campus near Cambridge in the UK, and our 850 staff are engineers, technicians, scientists and other professionals from all over the world.

EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation. The remuneration package comprises a competitive salary, a comprehensive pension scheme and health insurance, educational and other family related benefits where applicable, as well as financial support for relocation and installation. For more information about pay and benefits click here

We have an informal culture, international working environment and excellent professional development opportunities but one of the really amazing things about us is the concentration of technical and scientific expertise – something you probably won’t find anywhere else.

If you’ve ever visited the campus you’ll have experienced first-hand our friendly, collegial and supportive atmosphere, set in the beautiful Cambridgeshire countryside. Our staff also enjoy excellent sports facilities including a gym, a free shuttle bus, an on-site nursery, cafés and restaurant and a library.

What else you need to know

To view a copy of the full job description please click here

To apply please submit a covering letter and CV through our online system. Applications are welcome from all nationalities and this will continue after Brexit. For more information please see our website. Visa information will be discussed in more depth with applicants selected for interview.

EMBL-EBI is committed to achieving gender balance and strongly encourages applications from women, who are currently under-represented at all levels. Appointment will be based on merit alone.

Applications will close at 23:00 GMT on the date listed above.

  • Hinxton, UK
  • 10 Mar 2020

Job description

Ensembl (http://www.ensembl.org/) is one of the leading large-scale bioinformatics projects for genome annotation. We import ‘big’ amounts of ‘data’ from various archives (genome sequences, variation archives, etc), to create summaries (e.g. gene annotations, whole-genome alignments, gene trees, regulatory elements, etc.). We redistribute these freely to researchers across the world.

We are looking for an enthusiastic software developer to join our team. You will be responsible for developing and maintaining the very core of the apis used by Ensembl

Your role

You will

  • Design and develop APIs which are consumed by internal as well as external users for their computational workflows
  • Support and maintain the existing open source code
  • Co-ordinate answers for user queries
  • Contribute to modelling for seamless access of structured/non-structured data types
  • Help in development and maintenance of proprietary HPC based workflow manager system

You have

  • MSc or Phd or equivalent experience, in computer science/bioinformatics (or related field), large software development projects
  • Experience in object oriented Perl programming
  • Experience in database modelling and SQL
  • Ability to work on parallel tasks
  • Good communication skills
  • Ability to work independently while also interacting in a team environment
  • Attitude to contribute to a larger scientific cause

You might also have

  • Experience in development of scientific computational workflows
  • Working knowledge of HPC based workflows managers
  • Experience in working in large scientific projects

Why join us

At EMBL-EBI, we help scientists realise the potential of ‘big data’ in biology by enabling them to exploit complex information to make discoveries that benefit mankind.

Working for EMBL-EBI gives you an opportunity to apply your skills and energy for the greater good.

As part of the European Molecular Biology Laboratory (EMBL), we are a non-profit, intergovernmental organisation funded by over 27 member states and two associate member states.

We are located on the Wellcome Genome Campus near Cambridge in the UK, and our 850 staff are engineers, technicians, scientists and other professionals from all over the world.

EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation. The remuneration package comprises a competitive salary, a comprehensive pension scheme and health insurance, educational and other family related benefits where applicable, as well as financial support for relocation and installation. For more information about pay and benefits click here

We have an informal culture, international working environment and excellent professional development opportunities but one of the really amazing things about us is the concentration of technical and scientific expertise – something you probably won’t find anywhere else.

If you’ve ever visited the campus you’ll have experienced first-hand our friendly, collegial and supportive atmosphere, set in the beautiful Cambridgeshire countryside. Our staff also enjoy excellent sports facilities including a gym, a free shuttle bus, an on-site nursery, cafés and restaurant and a library.

What else you need to know

To view a copy of the full job description please click here

To apply please submit a covering letter and CV through our online system. Applications are welcome from all nationalities and this will continue after Brexit. For more information please see our website. Visa information will be discussed in more depth with applicants selected for interview.

EMBL-EBI is committed to achieving gender balance and strongly encourages applications from women, who are currently under-represented at all levels. Appointment will be based on merit alone.

Applications will close at 23:00 GMT on the date listed above.

  • Brighton, UK
  • £35k - 60k
  • 10 Mar 2020

Job description

Back End Developer (Node.JS/Perl) – Brighton – up to £60K + benefits

A leading UK Data Analytics company based in the heart of Brighton are looking to recruit a Back End Web Developer to work on the backend of their applications currently being rewritten onto Node.js and JavaScript. You will be based in their lovely offices in the heart of Brighton and this role will be working alongside a number of highly talented Developers on their core platform team.

This company are now looking for a Developer with a strong passion for coding performant backend applications to help us grow and maintain the product API’s and internal back office systems that drive their Data Analytics platform. This platform is core to the internet services of many of  the largest companies across the globe. 

As a Backend Developer, you will be part of the core experienced back-end engineering team, working on a large scale re-development project, so this is an opportunity to influence the platform and the business in a highly visible role. They are in the process of rewriting their back office from Perl to JavaScript so any experience with Perl would be advantageous but not essential.

It would be useful to have some of the following skills:

  • Prior experience with a scripting language (Python, Go or Perl) - Essential.
  • Understanding of Node.js – Essential
  • Database experience preferably MySQL.
  • Experience with Ubuntu, Vagrant and AWS would be a plus.

For the right candidate, there are opportunities to progress your career, work with some of the most exciting technology projects in the Brighton area and the chance to build incredible applications used by some of the biggest technology clients in the U.K and abroad.

If you would like to join one of the most exciting tech companies in Brighton and be a major part of their highly successful development team building innovative applications used by millions of people every day, then please get in touch to find out more?

  • Brighton, UK
  • £35k - 60k
  • 10 Mar 2020

Job description

Back End Developer (Node.JS/Perl) – Brighton – up to £60K + benefits

A leading UK Data Analytics company based in the heart of Brighton are looking to recruit a Back End Web Developer to work on the backend of their applications currently being rewritten onto Node.js and JavaScript. You will be based in their lovely offices in the heart of Brighton and this role will be working alongside a number of highly talented Developers on their core platform team.

This company are now looking for a Developer with a strong passion for coding performant backend applications to help us grow and maintain the product API’s and internal back office systems that drive their Data Analytics platform. This platform is core to the internet services of many of  the largest companies across the globe. 

As a Backend Developer, you will be part of the core experienced back-end engineering team, working on a large scale re-development project, so this is an opportunity to influence the platform and the business in a highly visible role. They are in the process of rewriting their back office from Perl to JavaScript so any experience with Perl would be advantageous but not essential.

It would be useful to have some of the following skills:

  • Prior experience with a scripting language (Python, Go or Perl) - Essential.
  • Understanding of Node.js – Essential
  • Database experience preferably MySQL.
  • Experience with Ubuntu, Vagrant and AWS would be a plus.

For the right candidate, there are opportunities to progress your career, work with some of the most exciting technology projects in the Brighton area and the chance to build incredible applications used by some of the biggest technology clients in the U.K and abroad.

If you would like to join one of the most exciting tech companies in Brighton and be a major part of their highly successful development team building innovative applications used by millions of people every day, then please get in touch to find out more?